{
  "_id": "6ad3165962c1581dfb2fa522",
  "Package": "adaptIVPT",
  "Type": "Package",
  "Title": "Adaptive Bioequivalence Design for In-Vitro Permeation Tests",
  "Version": "1.1.0",
  "Date": "2024-01-14",
  "Authors@R": "c(\nperson(\"Daeyoung\", \"Lim\", email = \"Daeyoung.Lim@fda.hhs.gov\",\nrole = c(\"aut\", \"cre\")),\nperson(\"Elena\", \"Rantou\", email = \"Elena.Rantou@fda.hhs.gov\", role = \"ctb\"),\nperson(\"Jessica\", \"Kim\", email = \"Jessica.Kim@fda.hhs.gov\", role = \"ctb\"),\nperson(\"Sungwoo\", \"Choi\", email = \"Sungwoo.Choi@fda.hhs.gov\", role = \"ctb\"),\nperson(\"Nam Hee\", \"Choi\", email = \"NamHee.Choi@fda.hhs.gov\", role = \"ctb\"),\nperson(\"Stella\", \"Grosser\", email = \"Stella.Grosser@fda.hhs.gov\", role = \"ctb\"))",
  "Maintainer": "Daeyoung Lim <Daeyoung.Lim@fda.hhs.gov>",
  "Description": "Contains functions carrying out adaptive procedures using\nmixed scaling approach to establish bioequivalence for in-vitro\npermeation test (IVPT) data. Currently, the package provides\nprocedures based on parallel replicate design and balanced\ndata, according to the U.S. Food and Drug Administration's\n\"Draft Guidance on Acyclovir\"\n<https://www.accessdata.fda.gov/drugsatfda_docs/psg/Acyclovir_topical%20cream_RLD%2021478_RV12-16.pdf>.\nPotvin et al. (2008) <doi:10.1002/pst.294> provides the basis\nfor our adaptive design (see Method B). For a comprehensive\noverview of the method, refer to Lim et al. (2023)\n<doi:10.1002/pst.2333>. This package reflects the views of the\nauthors and should not be construed to represent the views or\npolicies of the U.S. Food and Drug Administration.",
  "License": "GPL (>= 3)",
  "Encoding": "UTF-8",
  "LazyLoad": "yes",
  "RoxygenNote": "7.2.1",
  "NeedsCompilation": "yes",
  "Config/pak/sysreqs": "cmake libfreetype6-dev libglu1-mesa-dev make\ntexlive libpng-dev libuv1-dev libgl1-mesa-dev zlib1g-dev",
  "Repository": "https://daeyounglim.r-universe.dev",
  "Date/Publication": "2024-01-23 18:04:29 UTC",
  "RemoteUrl": "https://github.com/daeyounglim/adaptivpt",
  "RemoteRef": "HEAD",
  "RemoteSha": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
  "Packaged": {
    "Date": "2026-10-17 06:24:24 UTC",
    "User": "root"
  },
  "Author": "Daeyoung Lim [aut, cre],\nElena Rantou [ctb],\nJessica Kim [ctb],\nSungwoo Choi [ctb],\nNam Hee Choi [ctb],\nStella Grosser [ctb]",
  "_user": "daeyounglim",
  "_type": "src",
  "_file": "adaptIVPT_1.1.0.tar.gz",
  "_fileid": "https://r2.ropensci.org/a37c3dfb792b20a8010a2d1f756f19c83ba463697410c331d3f26ef5e196e1cb",
  "_filesize": 117068,
  "_sha256": "a37c3dfb792b20a8010a2d1f756f19c83ba463697410c331d3f26ef5e196e1cb",
  "_expires": "2027-01-25T06:31:52.000Z",
  "_created": "2026-10-17T06:24:24.000Z",
  "_published": "2026-10-17T06:31:53.577Z",
  "_buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_jobs": [
    {
      "job": 117329748272,
      "time": 169,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "12092342956"
    },
    {
      "job": 117329748377,
      "time": 161,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "12091914806"
    },
    {
      "job": 117329748357,
      "time": 124,
      "config": "linux-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "12091839989"
    },
    {
      "job": 117329748320,
      "time": 147,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "12091753535"
    },
    {
      "job": 117329748294,
      "time": 194,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "12092795936"
    },
    {
      "job": 117329748307,
      "time": 258,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "12092192717"
    },
    {
      "job": 117329748397,
      "time": 122,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "12092726243"
    },
    {
      "job": 117329748281,
      "time": 265,
      "config": "macos-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "12093015167"
    },
    {
      "job": 117329135266,
      "time": 187,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "12092635656"
    },
    {
      "job": 117329748322,
      "time": 187,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "12092019592"
    },
    {
      "job": 117329748292,
      "time": 349,
      "config": "windows-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "12092398025"
    },
    {
      "job": 117329748354,
      "time": 154,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "12092875517"
    },
    {
      "job": 117329748328,
      "time": 104,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "12092243824"
    },
    {
      "job": 117329748323,
      "time": 407,
      "config": "windows-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "12092920795"
    },
    {
      "job": 117329748288,
      "time": 101,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "12092104279"
    }
  ],
  "_upstream": "https://github.com/daeyounglim/adaptivpt",
  "_commit": {
    "id": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
    "author": "Daeyoung Lim <daeyounglim@daeyoungs-mbp.mynetworksettings.com>",
    "committer": "Daeyoung Lim <daeyounglim@daeyoungs-mbp.mynetworksettings.com>",
    "message": "fix whitespace in url\n",
    "time": 1706033069
  },
  "_maintainer": {
    "name": "Daeyoung Lim",
    "email": "daeyoung.lim@fda.hhs.gov",
    "login": "daeyounglim",
    "description": "",
    "uuid": 43422240
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.4",
      "role": "Depends"
    },
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "RcppArmadillo",
      "role": "LinkingTo"
    },
    {
      "package": "RcppProgress",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "role": "Imports"
    },
    {
      "package": "rgl",
      "role": "Imports"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    }
  ],
  "_owner": "daeyounglim",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 0,
  "_contributors": [
    {
      "user": "daeyounglim",
      "count": 13,
      "uuid": 43422240
    }
  ],
  "_userbio": {
    "uuid": 43422240,
    "type": "user",
    "name": "Daeyoung Lim",
    "followers": 11
  },
  "_downloads": {
    "count": 429,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/adaptIVPT"
  },
  "_devurl": "https://github.com/daeyounglim/adaptivpt",
  "_searchresults": 0,
  "_topics": [
    "openblas",
    "cpp",
    "openmp"
  ],
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/adaptIVPT.html",
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/manual.pdf",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md"
  ],
  "_homeurl": "https://github.com/daeyounglim/adaptivpt",
  "_realowner": "daeyounglim",
  "_cranurl": true,
  "_releases": [
    {
      "version": "1.0.0",
      "date": "2022-11-02"
    },
    {
      "version": "1.1.0",
      "date": "2024-01-26"
    }
  ],
  "_exports": [
    "msabe",
    "prms",
    "PRsurface",
    "rss"
  ],
  "_help": [
    {
      "page": "adaptIVPT",
      "title": "adaptIVPT: Adaptive Bioequivalence Design for In-Vitro Permeation Tests for Pharmacokinetics with Mixed Scaling Approach",
      "topics": [
        "adaptIVPT"
      ]
    },
    {
      "page": "msabe",
      "title": "Run the mixed scaling approach in bioequivalence (BE) studies",
      "topics": [
        "msabe"
      ]
    },
    {
      "page": "prms",
      "title": "Compute the passing rate for the mixed scaling approach in bioequivalence (BE) studies",
      "topics": [
        "prms"
      ]
    },
    {
      "page": "PRsurface",
      "title": "Plot the passing-rate curve and the passing-rate surface in IVPT",
      "topics": [
        "PRsurface"
      ]
    },
    {
      "page": "rss",
      "title": "Reestimate the sample size for the adaptive design in bioequivalence (BE) studies using mixed criterion.",
      "topics": [
        "rss"
      ]
    },
    {
      "page": "summary.msabe",
      "title": "`summary` method for class \"`msabe`\"",
      "topics": [
        "summary.msabe"
      ]
    }
  ],
  "_readme": "https://github.com/daeyounglim/adaptivpt/raw/HEAD/README.md",
  "_rundeps": [
    "base64enc",
    "bslib",
    "cachem",
    "cli",
    "digest",
    "evaluate",
    "fastmap",
    "fontawesome",
    "fs",
    "highr",
    "htmltools",
    "htmlwidgets",
    "jquerylib",
    "jsonlite",
    "knitr",
    "lifecycle",
    "magrittr",
    "memoise",
    "mime",
    "R6",
    "rappdirs",
    "Rcpp",
    "RcppArmadillo",
    "RcppProgress",
    "rgl",
    "rlang",
    "rmarkdown",
    "sass",
    "tinytex",
    "xfun",
    "yaml"
  ],
  "_sysdeps": [
    {
      "shlib": "libblas",
      "package": "libopenblas0-pthread",
      "source": "openblas",
      "version": "0.3.32+ds-5",
      "name": "openblas",
      "homepage": "https://www.openblas.net/",
      "description": "Optimized BLAS (linear algebra) library (shared lib, pthread)"
    },
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "16-20260322-1ubuntu1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    },
    {
      "shlib": "libgomp",
      "package": "libgomp1",
      "source": "gcc",
      "version": "16-20260322-1ubuntu1",
      "name": "openmp",
      "homepage": "http://gcc.gnu.org/",
      "description": "GCC OpenMP (GOMP) support library"
    }
  ],
  "_score": 2.6989700043360187,
  "_indexed": true,
  "_nocasepkg": "adaptivpt",
  "_universes": [
    "daeyounglim"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.1.0",
      "date": "2026-10-17T06:27:15.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/75a7d7902eb7203c89907c4dae2202724e9d1af8d0148d0d73e23f59ae1951f4",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.1.0",
      "date": "2026-10-17T06:27:05.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/ebfa9910bd7521fc9519b37c57a11b4e2cd9305454817ec9500478337e131347",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.1.0",
      "date": "2026-10-17T06:26:39.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/6fe18ca267e7d0db0c390d7535c8f65dcf86269a7067b55caac5766eccc122c0",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.1.0",
      "date": "2026-10-17T06:27:02.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/3877561929b2a24144d1b6cc1f31db8fde2d45fcdde9879fc171deaab930ae19",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.1.0",
      "date": "2026-10-17T06:27:13.000Z",
      "arch": "aarch64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/d8b602f50e1fcdf1723063dda962d0828d6b2c4185413f9445acd54a62e7fca5",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.1.0",
      "date": "2026-10-17T06:28:03.000Z",
      "arch": "x86_64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/a8a04f4bb91fffc76f9751afbad5b446b137aaf7b4ccf7028f9b88c28b0e4cd9",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.1.0",
      "date": "2026-10-17T06:26:32.000Z",
      "arch": "aarch64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/645123691eced0598c5cbfe5b42541e782661b3c7698adab3e9a7bd6cc109d5d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.1.0",
      "date": "2026-10-17T06:28:03.000Z",
      "arch": "x86_64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/f987abee188c726992414585669c7e1831d5c7517764cd86583d349d132860a7",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.1.0",
      "date": "2026-10-17T06:27:44.000Z",
      "arch": "emscripten",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/5b2a67b00a37ce2279ba52c6c075513fb6623933cdf6cdc08cc8fe732f1fd529",
      "status": "success",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.1.0",
      "date": "2026-10-17T06:29:26.000Z",
      "arch": "aarch64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/f1f78a9801b27950a7ee92e73a3d4df6b013e5838ccae2aa970f4b95bb0263ec",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.1.0",
      "date": "2026-10-17T06:25:47.000Z",
      "arch": "x86_64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/99158ae55a36f250f1c05cf32ffa17a1acbd738ef3b9dffc9615b5ca2083f8b7",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.1.0",
      "date": "2026-10-17T06:25:39.000Z",
      "arch": "x86_64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/7db16ff8351da8ca4edd065c525003f6e41f9fccb5190945626ea3eefb4ad735",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.1.0",
      "date": "2026-10-17T06:30:36.000Z",
      "arch": "aarch64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/513ae80c1de16a93853f719a38a3f9f497f7af24f43ac63e58de9fc167d6dc8d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.1.0",
      "date": "2026-10-17T06:25:37.000Z",
      "arch": "x86_64",
      "commit": "f7c1e8c8264b324a143e28b9d8af0c4e06985dfa",
      "fileid": "https://r2.ropensci.org/9373c5c564d93c442fa0ba959910dc6738fe0e95913bb5624c78d154535efd19",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/daeyounglim/actions/runs/39009599782"
    }
  ]
}